'40-Year-Old Virgin' on top

In "The 40-Year-Old Virgin" Steve Carell plays Andy Stitzer, a dedicated collector of fantasy action figures who rides his bike to work at an electronics store and, after hours, watches TV's Survivor with elderly neighbors. He has had a few girlfriends, but things never quite took off romantically. Over the years, his bad luck with women has morphed into resignation.

"The Brothers Grimm" opened in second place, earning about 15 million dollars, according to the Los Angeles-based box office tracking firm Exhibitor Relations Co. Inc.

"Red Eye" was third with 10.4 million dollars, followed by "Four Brothers" (7.8 million) and "Wedding Crashers" (6.25 million).