Jennifer Aniston's close relationship Courteney Cox could end her marriage.

According to gossips, David Arquette (Cox's husband) has given Courteney an ultimatum - it's "me or Aniston".

Courteney and Jennifer - who have been friends since meeting on the set of Friends 13 years ago - are virtually inseparable, with Jennifer Aniston joining her friend for U.S. public holidays and even tagging along on 'romantic' breaks with her husband.

But now David has had enough of sharing his wife with another woman and is laying down the law.

A source said: "Somewhat understandably, David's now saying it's him or Jennifer. He's had enough and is drawing a line in the sand.

“He's asking that Jennifer's visits become less frequent and that there are no phone calls between midnight and 8am."