He said: "I think it must be harder to be female than male. Apart from having to deal with period pains, pregnancy and child birth, I think women are more emotional than men. It's not just that they find it easier to talk about emotions, I think they actually feel emotions more deeply."
The 32-year-old singer, who has been in a relationship with former tennis player Anna Kournikova for the past five years, also revealed he gets on better with girls than men.
He said: "I'm as comfortable with women as I am with men. Of my closest friends, three are men and two are women.
"I learned a lot about women from my mother and my nanny, but I don't think you really get to know what makes women tick until you have a romantic relationship."
Despite claiming to get on well with women, Enrique isn't a very romantic man.
He said: "Like most men, I'm not very good at romantic gestures."